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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  5

Year :  2012

Pages :   635-640

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Formulation and Evaluation of Oral Suspension of Oseltamivir Phosphate Using Different Vehicle



Address:   Dharmendra Singh Sisodiya*, Anuraj Soni, Ronak Patel, Uma Sankar Rao Majji, Praveen Khirwadkar
B.N. College of Pharmacy, Udaipur (Raj.)
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Oseltamivir phosphate is used in the treatment and prophylaxis of both influenza A and influenza B. Oseltamivir is readily absorbed from the gastrointestinal tract after oral administration of oseltamivir phosphate and is extensively converted predominantly by hepatic esterases to oseltamivir phosphate. At least 75% of an oral dose reaches the systemic circulation as oseltamivir phosphate. Exposure to oseltamivir is less than 5% of the total exposure after oral dosing. So in oral dosage form it give high bioavability. A wide choice of vehicles ranging for oral suspension development .for a good dosage form must important of choosing of a good vehicle.
KEYWORDS:
Oseltamivir phosphate, vehicle, oral suspension, dosage form.
Cite:
Dharmendra Singh Sisodiya, Anuraj Soni, Ronak Patel, Uma Sankar Rao Majji, Praveen Khirwadkar. Formulation and Evaluation of Oral Suspension of Oseltamivir Phosphate Using Different Vehicle. Research J. Pharm. and Tech. 5(5): May2012; Page 635-640.
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