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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  5

Year :  2012

Pages :   570-579

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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An overview on Combinatorial Chemistry



Address:   P. Jitendra Kumar1*, P. Sivannarayana1, V. Saikishore2, S. Sri Hariteja1, Syed Sharif1, M. Bhaskar1, U. Kalyan1
1Nalanda Institute of Pharmaceutical Sciences Kantepudi, Sattenapalli, Guntur (Dt), A.P.
2Bapatla College of Pharmacy, Bapatla, Guntur (Dt) A.P.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Combinatorial chemistry is a new methodology by which we can simultaneously synthesize a large number of possible and defined compounds that could be formed from a number of building blocks (starting materials) which are screened for pharmacological activity. This combinatorial chemistry technique has been explored as an alternative to conventional approaches for the synthesis of compounds in the drug discovery process. The combinatorial techniques are developed in accordance to the increased advancements in the screening methods such as high throughput screening. This article also tries to present pros and cons the combinatorial chemistry, some of the advances made in recent years and their applications and screening methods for the combinatorial libraries
KEYWORDS:
Combinatorial chemistry, High Throughput screening, solid phase, Solution phase.
Cite:
P. Jitendra Kumar, P. Sivannarayana, V. Saikishore, S. Sri Hariteja, Syed Sharif, M. Bhaskar, U. Kalyan. An overview on Combinatorial Chemistry. Research J. Pharm. and Tech. 5(5): May2012; Page 570-579.
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