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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  4

Year :  2012

Pages :   513-517

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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In – vitro antioxidant activity of aqueous and ethanolic extract of Coscinium fenestratum root and Embelia ribes flower



Address:   Basavaraj H 1 , Purnima Ashok. 2
1Government College of Pharmacy, Bangalore.
2KLE University’s College of Pharmacy, Bangalore.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study envisaged to evaluate in-vitro anti oxidant activity of ethanolic and aqueous extracts of roots of Coscinium fenestratum and extracts of Embelia ribes flower, by estimating nitric oxide scavenging activity, ferric thiocynate and total reduction capacity and carrying out DPPH assay of increasing concentration of extracts and compared with ascorbic acid, in view of investigations of pharmacological activities reported, extensive chemistry and being a part of folklore medicine. Review of literature revealed paucity of reports of in- vitro study of parts and extract chosen for the study. Results revealed concentration dependent increase in nitric oxide, DPPH free radical, ferric thiocyanate inhibition / scavenging activity, and similar total reduction capacity, indicated by increase in absorbance by ethanolic and aqueous extracts of roots of Coscinium fenestratum and of Embelia ribes flower. Ethanolic extracts possess relatively higher scavenging activity than aqueous extracts. The results identifies for the first time, the ethanolic and aqueous extracts of roots of Coscinium fenestratum and extracts of Embelia ribes flower, possess in-vitro antioxidant activity.
KEYWORDS:
in-vitro, antioxidant, Free radicals, Coscinium fenestratum root, Embelia ribes flower.
Cite:
Basavaraj H, Purnima Ashok. In – vitro antioxidant activity of aqueous and ethanolic extract of Coscinium fenestratum root and Embelia ribes flower. Research J. Pharm. and Tech. 5(4): April 2012; Page 513-517.
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