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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  3

Year :  2012

Pages :   369-375

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Fluorescence Properties of Schiff Bases of 2-chloro-3-formylquinoline



Address:   B. R. Thorat, M. Mustapha, D. Khandekar, Swati Lele, P. Kamat, S. Sawant, R. Jadhav, D. Shelke, Shivaji Kolekar, R. G. Atram and R. Yamgar
P. G. Dept of Chemistry, Govt. of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
A simple and regioselective synthesis of 2-chloro-3-formylquinoline [1] by the cyclisation of N-aryacetamide has been reported by the Vilsmeier Haack reaction/cyclisation. 2-Chloro-3-formylquinoline, the formyl group shows condensation with variety of haloanilines & hydrazones and forming schiff bases N-[(E)-(2-chloroquinolin-3-yl)methylidene]anilides [2a-e] which are further subjected to fluorescence study.
KEYWORDS:
Haloanilines, Formylation, Vilsmeier Haack reaction, quinoline, Schiff bases.
Cite:
B. R. Thorat, M. Mustapha, D. Khandekar, Swati Lele, P. Kamat, S. Sawant, R. Jadhav, D. Shelke, Shivaji Kolekar, R. G. Atram, R. Yamgar. Synthesis and Fluorescence Properties of Schiff Bases of 2-chloro-3-formylquinoline. Research J. Pharm. and Tech. 5(3): March 2012; Page 369-375.
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