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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  2

Year :  2012

Pages :   143-151

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Novel Fast Disintegrating Tablet: A Review



Address:   Deepali Avinash Meher*
Department of Pharmaceutics Rajarambapu College of Pharmacy, Kasegaon, Tal: Walwa Dist:Sangli Pin:415404
Corresponding author
DOI No: Not Available

ABSTRACT:
Drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and biochemical parameters pertinent to their performance. Over the past three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. Products of ODT technologies entered the market in the 1980s, have grown steadily in demand, and their product pipelines are rapidly expanding. New ODT technologies address many pharmaceutical and patient needs, ranging from enhanced life-cycle management to convenient dosing for pediatric, geriatric, and psychiatric patients with dysphasia. This has encouraged both academia and industry to generate new orally disintegrating formulations and technological approaches in this field. The aim of this article is to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects.
KEYWORDS:
fast dissolving, superdisintegrants, disintegration, evaluation.
Cite:
Deepali Avinash Meher. Novel Fast Disintegrating Tablet: A Review. Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 143-151.
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