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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  12

Year :  2012

Pages :   1490-1496

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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1,2,4-Oxadiazoles: A potential pharmacological agents-An overview

Address:   Ajay Kumar K.1*, Lokeshwari D.M.1, Pavithra G.2 and Vasanth Kumar G.1
1Post Graduate Department of Chemistry, Yuvaraja’s College, University of Mysore, Mysore, India.
2Department of Chemistry, JSS College for Women, Saraswathipuram, Mysore, India.
*Corresponding Author
DOI No: Not Available

Drug discovery and development is a multidisciplinary, creative, innovative and highly regulated process. Finding a successful lead has been a great challenge in pharmaceutical research and is utmost important in the formulation development. Optimization of the process used to manipulate the compound to improve its chemical stability, potency, biological or therapeutic effectiveness. Literature survey reveals 1,2,4-oxadiazoles are statistically significant in bioorganic and pharmaceutical chemistry. They were known to exhibit varied pharmacological properties. This review article provides up to date information about developments, exploration of new methods, techniques adopted for the synthesis of 1,2,4-oxadiazoles, their transformation to biologically important derivatives, and studies on their pharmacological properties.
Amidoximes, oxadiazoles, antitumour, antioxidant, antiinflammatory.
Ajay Kumar K., Lokeshwari D.M., Pavithra G., Vasanth Kumar G. 1,2,4-Oxadiazoles: A potential pharmacological agents-An overview. Research J. Pharm. and Tech. 5(12): Dec. 2012; Page 1490-1496.
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