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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  11

Year :  2012

Pages :   1396-1401

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Pharmacological studies of Stem Bark Extracts of Zanthoxylum tetraspermum Wight and Arn



Address:   V.R. Ravikumar1*, V. Gopal2 and T. Sudha3
1Research Scholar, Sastra University Thanjavur. Tamil Nadu.
Department of Pharmacognosy, The Erode college of Pharmacy. Erode.
2Mothertheresa Post Graduate Research Institute of Health Sciences, Pondicherry.
3Department of Pharmaceutical Analysis, The Erode College of Pharmacy and Research, Erode-638112. Tamil Nadu.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Present study was undertaken to examine anti inflammatory, analgesic and wound healing activity of ethanolic and aqueous extracts of Zanthoxylum tetraspermum Wight and Arn. Ethanolic and aqueous extracts shows significant anti inflammatory (Carrageenan induced pawn oedema model), analgesic (Hot plate and acetic acid induced model) and wound healing (Excision wound model) activity when compared to the standard like Indomethacin (10mg/kg p.o). Pentazocine, (30mg/kg, i.p.) Indomethacin (5mg/kg), metrozyl gel. respectively. Ethanolic extract shows more significant activities when compared to aqueous extract of bark of Zanthoxylum tetraspermum Wight and Arn at different dose level.
KEYWORDS:
Zanthoxylum tetraspermum Wight and Arn, analgesic, anti-inflammatory, wound healing, Aqueous and Ethanolic extract.
Cite:
V.R. Ravikumar, V. Gopal, T. Sudha. Pharmacological studies of Stem Bark Extracts of Zanthoxylum tetraspermum Wight and Arn. Research J. Pharm. and Tech. 5(11): Nov. 2012; Page 1396-1401.
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