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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  9

Year :  2011

Pages :   1436-1438

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Antiulcer Activity of Leaf Extract of Lawsonia inermis in Albino rats



Address:   Venkateshwarlu Goli1*, Sravan Prasad Macharla2, K. Vijaya Bhasker1, N.L Gowrishankar3, J. Bhaskar1, and Ch. Dhanalakshmi4
1Department of Pharmacognosy, Venkateshwara Institute of Pharmaceutical Sciences, Charlapally , Nalgonda, Andhra Pradesh, India – 508001
2GBN Institute of Pharmacy, Ghatkesar, RR District, Andhra Pradesh, India.
3Department of Pharmacognosy, Swami Viveka Nanda Institute of Pharmaceutical Sciences, Bhuvanagiri, Nalgonda Andhra Pradesh, India – 508001
4Holy Mary Institute of Technology and Sciences, RR District, Andhra Pradesh, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present work was evaluated anti-ulcer potential of the ethanol extract of leaf of Lawsonia inermis against in vivo indomethacin- induced gastric ulcer using pylorus ligation method. All the dose of the leaf extract (100, 200 and 400 mg/kg) significantly (P?0.01) reduced the ulcer index in this experiment. In conclusion, the present study provides preliminary data on the antiulcer potential of Trianthema portulacastrum leaf and support the traditional uses of the plant for the treatment of gastric ulcer.
KEYWORDS:
Lawsonia inermis leaf, ethanol extract, gastric ulcer, pylorus ligation, indomethacin, induced gastric ulcers, ulcer index.
Cite:
Venkateshwarlu Goli, Sravan Prasad Macharla, K. Vijaya Bhasker, N.L Gowrishankar, J. Bhaskar, Ch. Dhanalakshmi. Antiulcer Activity of Leaf Extract of Lawsonia inermis in Albino rats. Research J. Pharm. and Tech. 4(9): Sept. 2011; Page 1436-1438.
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