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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  8

Year :  2011

Pages :   1224-1226

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Antioxidant and Free Radical Scavenging Activity of Ethanolic Extract of Morinda citrifolia



Address:   Ranju Pal1*, Kundlik Girhepunje2, Nidhi Shrivastava1, Mohammed Misbah Hussain1 and Thirumoorthy N3
1NIMS University, Jaipur, (Rajasthan)
2Radharaman College of Pharmacy, Bhopal (M.P.).
3Cherraan’s College of Pharmacy, Coimbatore (Tamil Nadu)
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The aim of this work was to estimate the total phenolic and flavonoid content, and to evaluate in-vitro antioxidant activity of ethanolic root extract of Morinda citrifolia (MCREt). The raw, dry root powder was extracted with 99.9% of ethanol. Phytochemical test shows that extract contains higher level of total phenol and flavonoids. Total phenolic compound in ethanolic root extract of Morinda citrifolia was found to be 92 mg/g of extract calculated as gallic acid equivalent (r2=0.9976) and total flavonoids compound was found to be 36 mg/g of extract calculated as rutin equivalent (r2=0.9985). The extract was screened for its potential antioxidant activities using tests such as hydroxyl radical-scavenging activity, reducing power activity, and hydrogen peroxide-scavenging activity. The in-vitro antioxidant assay showed MCREt posses potent antioxidant activity when compared with reference compound butylated hydroxytoluene (BHT). MCREt could be useful for preparation of neutraceuticals as potent antioxidant to treat various human diseases and its complications.
KEYWORDS:
In vitro antioxidant activity, Phenol, Flavonoid, Reducing power activity, Hydrogen peroxide-scavenging activity, Morinda citrifolia
Cite:
Ranju Pal, Kundlik Girhepunje, Nidhi Shrivastava, Mohammed Misbah Hussain, Thirumoorthy N. Antioxidant and Free Radical Scavenging Activity of Ethanolic Extract of Morinda citrifolia. Research J. Pharm. and Tech. 4(8): August 2011; Page 1224-1226.
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