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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  8

Year :  2011

Pages :   1250-1251

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Spectrophotometric Estimation of Milnacipran in Pharmaceutical Formulation



Address:   Kiran Kumar V.1, V. Srivani1, K. Vanitha Prakash1, B. Mohammed Ishaq1 and M. Padmalatha2
1SSJ College of Pharmacy, V.N. Pally, Gandipet, Hyderabad (India).
2Vijaya College of Pharmacy, Hayathnagar, Hyderabad
*Corresponding A
DOI No: Not Available

ABSTRACT:
One simple, economical, precise, reliable and reproducible Visible Spectrophotometric Method has been developed for the estimation of Milnacipran (MCP) in bulk as well as in capsule formulations. The developed Method was based on the formation of chloroform extractable complex of Milnacipran with Bromocresol Green (BCG) which shows maximum absorption at 412nm. The absorbance-concentration plot is linear over the range 50-500µg/ml. The different experimental parameters effecting the development and stability were studied carefully and optimized. A result of analysis for the method was validated statistically and recovery studies were performed.
KEYWORDS:
Milnacipran (MCP), Bromocresol Green (BCG), Ultraviolet-Visible double beam spectrophotometer.
Cite:
Kiran Kumar V., V. Srivani, K. Vanitha Prakash, B. Mohammed Ishaq, M. Padmalatha. Spectrophotometric Estimation of Milnacipran in Pharmaceutical Formulation. Research J. Pharm. and Tech. 4(8): August 2011; Page 1250-1251.
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