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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  7

Year :  2011

Pages :   1082-1085

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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In Vitro Antioxidant Activity of Fruit of Benincasa hispida Cogn.



Address:   Manoj S. Pagare*, Hardik Joshi, Leena Patil and Vilasrao J. Kadam
Department of Pharmacology, Bharati Vidyapeeth’s College of Pharmacy, Sector 8, C.B.D., Belapur, Navi Mumbai 400614, Maharashtra, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Antioxidant based drugs or formulations for the prevention and treatment of complex diseases like atherosclerosis, stroke, diabetes, Alzheimer’s disease and cancer have appeared during the last three decades. Reactive oxygen species (ROS) play an important role in oxidative stress related to the pathogenesis of various important diseases. Antioxidants are substances that delay or prevent the oxidation of cellular oxidizable substrates. Recently, natural plants have received much attention as sources of biological active substances including antioxidants. The present study was undertaken to investigate the antioxidant activity of Benincasa hispida Cogn. Fruit. The in vitro antioxidant activity of the ethanol extract of the fruit of Benincasa hispida Cogn. was evaluated using various experimental methods such as H2O2 radical scavenging activity, DPPH free radical scavenging activity, nitric oxide radical scavenging activity and reducing power assay. The study suggests that the Benincasa hispida could be pharmaceutically exploited for antioxidant properties.
KEYWORDS:
Antioxidant, fruit of Benincasa hispida Cogn., H2O2 Assay, DPPH Assay, Nitric Oxide Assay, Reducing Power Assay.
Cite:
Manoj S. Pagare, Hardik Joshi, Leena Patil, Vilasrao J. Kadam. In Vitro Antioxidant Activity of Fruit of Benincasa hispida Cogn. Research J. Pharm. and Tech. 4(7): July 2011; Page 1082-1085.
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