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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  6

Year :  2011

Pages :   979-981

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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In Vivo Efficacy Study of Aceclofenac Gel Containing Linseed Oil and Ginger Oleoresin



Address:   Aejaz Ahmed1*, Sameer S. Sheaikh2 and Aijaz A. Sheikh 3
1Department of Pharmacology, A.A. College of Pharmacy, Akkalkuwa, Maharashtra, India,
2Department of Pharmacology, P.W. College of Pharmacy, Yavatmal, Maharashtra, India,
3Department of Pharmacology, Anuradha College of Pharmacy, Chikhli, Maharashtra, India,
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Aceclofenac is a Non-Steroidal Anti-Inflammatory Drug (NSAID), used in the treatment of inflammation and degenerative disorder of the musculoskeletal system. It is widely prescribed for the treatment of osteoarthritis, rheumatoid arthritis, dysmenorrheal, acute lumbago, musculoskeletal trauma and gonalgia (Knee pain). Aceclofenac is well tolerated, with most adverse events being minor and reversible and affecting mainly the G.I system. Most common events include dyspepsia, abdominal pain, nausea, ulcerative stomatitis and pancreatitis. In present study anti inflammatory activity of aceclofanac gel containing linseed oil and ginger oleoresin was checked by using Albino rats (Strain Wistar). It was found that aceclofanac gel containing 3% linseed oil, 1.5% ginger oleoresin and 10% methyl salicylate shows 81.16% edema inhibition in 3rd hour as compare to marketed Nusaid gel which shows 76.74% edema inhibition.
KEYWORDS:
Aceclofenac gel, Anti inflammatory, linseed oil, ginger oleoresin, In vivo
Cite:
Aejaz Ahmed, Sameer S. Sheaikh, Aijaz A. Sheikh. In Vivo Efficacy Study of Aceclofenac Gel Containing Linseed Oil and Ginger Oleoresin. Research J. Pharm. and Tech. 4(6): June 2011; Page 979-981.
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