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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  6

Year :  2011

Pages :   965-971

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Formulation and Evaluation of Chlorpheniramine Maleate from Methyl Cellulose Patches



Address:   Bagyalakshmi J.*, Nipu Sam P., George and Ravi T.K.
Sri Ramakrishna Institute of Paramedical Sciences, College of Pharmacy, Coimbatore-44.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Administration of drugs through skin has received great attention through the last decade. Hence this study aims to formulate an anti- histaminic drug – chlorpheniramine maleate (CPM) as transdermal patch using methyl cellulose - a bioadhesive polymer with dibutylphthalate (DBP) as plasticizer. Patches were prepared through solvent evaporation method, subjected for various evaluations including in vitro dissolution and in vitro permeation. The above evaluations of transdermal patches promises that CPM can be developed successfully as transdermal patches as an alternative route of administration fulfilling the objectives of this research work.
KEYWORDS:
Transdermal patch, chlorpheniramine maleate, polymers, bioadhesive.
Cite:
Bagyalakshmi J., Nipu Sam P., George, Ravi T.K. Formulation and Evaluation of Chlorpheniramine Maleate from Methyl Cellulose Patches. Research J. Pharm. and Tech. 4(6): June 2011; Page 965-971.
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