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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   756-758

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Preliminary Phytochemical Screening and Anthelmintic Activity of Acacia sinuata (Lourr.) Merr against Intestinal Helminthiasis



Address:   Thube Smita* , Baig R. Samrana and Gulam Mohammed Sifarish Ali
Department of Pharmacognosy, M. C. E. Society’s Allana College of Pharmacy, Azam Campus , 2390 K.B.Hidyatullah road, Camp, Pune 411 001. India
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Extracts from the pods of Acacia sinuata (Lourr.) Merr were investigated for their anthelmintic activity against Perithima posthuma taking into consideration their traditional use and reported chemical constituents. Various concentrations (10-100 mg/ml) of each extract were tested in the bioassay, which involved determination of time of paralysis and time for death of the worms. The activity of methanolic and ethyl acetate extracts were found to be more significant than the standard even at a dose of 10 mg/ml. Piperazine citrate (10 mg/ml) was used as standard reference and distilled water as control. The preliminary phytochemical screening showed the presence of carbohydrates, alkaloids and saponins.
KEYWORDS:
Acacia sinuate, Anthelmintic, Phytochemical screening, Steroids.
Cite:
Thube Smita , Baig R. Samrana, Gulam Mohammed Sifarish Ali. Preliminary Phytochemical Screening and Anthelmintic Activity of Acacia sinuata (Lourr.) Merr against Intestinal Helminthiasis. Research J. Pharm. and Tech. 4(5): May 2011; Page 756-758.
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