List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   735-738

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Simultaneous Estimation of Amlodipine besylate and Perinopril erbumine by UV Spectrophotometric Method



Address:   Shweta Purohit Nayak* and Sujit Pillai
GRY Institute of Pharmacy, Borawan, Khargone
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Two simple, accurate, precise, reproducible, requiring no prior separation and economical procedures for simultaneous estimation of Amlodipine Besylate and Perindopril Erbumine in tablet dosage form have been developed. First method employs formation and solving of simultaneous equation using 237 nm and 206 nm as two analytical wavelengths for both drugs in methanol. The second method is Q value analysis based on measurement of absorptivity at 227 nm (as an iso-absorptive point) and 237 nm. Beer’s law obeyed in concentration range of 5-40 µg/ ml and 15-60 µg/ ml for Amlodipine and perindopril respectively. Recovery studies was found close to100 % for Amlodipine Besylate and Perindopril Erbumine for both the methods. The proposed method is recommended for routine analysis of both the drugs in combined dosage form.
KEYWORDS:
Amlodipine Besylate (AB), Perindopril erbumine(PE), Simultaneous equation method, Q analysis.
Cite:
Shweta Purohit Nayak, Sujit Pillai. Simultaneous Estimation of Amlodipine besylate and Perinopril erbumine by UV Spectrophotometric Method. Research J. Pharm. and Tech. 4(5): May 2011; Page 735-738.
[View HTML]      [View PDF]



Visitor's No. :   264012