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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  4

Year :  2011

Pages :   555-557

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Evaluation of Suspending Properties of Combined Seed Mucilage



Address:   S.G. Killedar1*, R.G. Desai1, P.C. Deokate1 and R.S. Adnaik2
1Bharati Vidyapeeth College of Pharmacy, Kolhapur (MS) India
2Rajarambapu College of Pharmacy, Kasegaon, Sangli (MS) India
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Suspension is coarse dispersion of fine insoluble particles dispersed in liquid medium. To overcome the problem of inadequate dispersion of fine particles in vehicle, settling of dispersed particles and caking in suspension, suspending agents are used. Some suspending agents from natural and synthetic origin are currently available for the formulation of Pharmaceutical suspensions. Synthetic additives suffer from the problems of toxicity, incompatibility, feasibility and they also have high cost. But vegetable additives will provide best solution to the aforesaid problems of synthetic additives. The purpose of this study is to search for a cheap and effective natural suspending agent that can be used as an effective alternative for the formulation of pharmaceutical suspensions. Hence present work is undertaken to evaluate combined mucilage extracted from seeds of Ocimum basilicum, Plantago ovata and Lepodium sativum, for its suspending properties. The individual as well as combined seed mucilages have not shown any toxicity in tested animals. The combined seed mucilage has shown better suspending property at 2.5% level than sodium CMC.
KEYWORDS:
seed mucilage, degree of flocculation, suspending agents.
Cite:
S.G. Killedar, R.G. Desai, P.C. Deokate, R.S. Adnaik. Evaluation of Suspending Properties of Combined Seed Mucilage. Research J. Pharm. and Tech. 4(4): April 2011; Page 555-557.
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