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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  4

Year :  2011

Pages :   589-591

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Development and Validation of Spectrophotometric Method for Mesalamine in Pure and In Tablets



Address:   Lalit Jejurkar*, K.K.Tapar, M.D.Game, Tushar Birari and Gokul Ghenge
Vidyabharti College of Pharmacy, Department of P.G. and Research, Amravati-4446021
*Corresponding Author
DOI No: Not Available

ABSTRACT:
A simple UV spectrophotometric method for the analysis of Mesalamine was developed to analyze the drug in bulk and in tablet formulation. In this method the simple UV spectrum of mesalamine in phosphate buffer pH 6.8 was obtained which exhibits absorption maxima (? max) at 331.0 nm. The Beers law ranges was followed in the concentration range of 5-100 µg/ml. The proposed method does not require any separation of soluble excipients as they do not influence at the selected wavelength and assay conditions.
KEYWORDS:
Mesalamine, Spectrophotometric Method, Phosphate buffer pH-6.8.
Cite:
Lalit Jejurkar, K.K.Tapar, M.D.Game, Tushar Birari, Gokul Ghenge. Development and Validation of Spectrophotometric Method for Mesalamine in Pure and In Tablets. Research J. Pharm. and Tech. 4(4): April 2011; Page 589-591.
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