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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  3

Year :  2011

Pages :   723-427

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Compatibility Study of Aceclofenac and Tablet Disintegrants by Thermal and Nonthermal Methods



Address:   Monica R.P. Rao2, Devidas G. Bachhav1*, Ramdas B. Rode3, Komal R. Nikam1 and Namrata D. Pathade1
1MGV’s S.P.H.College of Pharmacy, Malegaon, Dist: Nashik, Maharashtra.
2AISSSMS College of Pharmacy, Pune, Maharashtra
3R.G. Sapkal College of Pharmacy, Nashik, Maharashtra
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Drug excipients compatibility study is important preformulation tool for the selection of excipients prior to large scale development trials, thereby helpful to avoid potential stability problems. The present investigation was aimed at Compatibility study of Aceclofenac, an NSAID with some tablet disintegrants as Starch 1500, Croscarmellose Sodium and Sodium starch glycolate, by thermal method (Differential Scanning Calorimetry) and results of DSC were confirmed by nonthermal methods (IR and Assay).
KEYWORDS:
Compatibility study, DSC, IR, Excipients, Thermal, Nonthermal.
Cite:
Monica RP Rao, Devidas G Bachhav, Ramdas B Rode, Komal R Nikam, Namrata D Pathade. Compatibility Study of Aceclofenac and Tablet Disintegrants by Thermal and Nonthermal Methods. Research J. Pharm. and Tech. 4(3): March 2011; Page 423-427.
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