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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  3

Year :  2011

Pages :   411-412

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Antihelmintic Activity of Methanol Extract of Gamma Irradiated and Unirradiated Citrus medica Fruit Bio-Mass



Address:   S.L. Munne1*, D.V. Parwate1, V.N. Ingle1 and M.A. Kamble2
1Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, 440 033 (M.S), INDIA.
2Department of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, 440 033 (M.S), INDIA
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study was undertaken to evaluate anthelmintic activity of methanolic extract of irradiated and unirradiated Citrus medica fruit bio-mass belonging to Rutaceae family using Pheretima posthuma as test worms. Various concentrations (10-50 mg/ml) of methanolic extracts were tested in the bioassay, which involved determination of time of paralysis (P) and time of death (D) of the worms. Piperazine citrate was taken as standard reference and distilled water as control. The results of present study indicated that the unirradiated extract significantly demonstrated paralysis and death of worms in less time as compare to radiated sample at higher concentration of 50 mg/ml.
KEYWORDS:
Anthelmintic, Citrus medica, Pheretima posthuma, Piperazine citrate.
Cite:
SL Munne, DV Parwate, VN Ingle, MA Kamble. Antihelmintic Activity of Methanol Extract of Gamma Irradiated and Unirradiated Citrus medica Fruit Bio-Mass. Research J. Pharm. and Tech. 4(3): March 2011; Page 411-412.
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