Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   189-196

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Nasal Medication: A Potential Alternative Route

Address:   Sharma Akshat*, Pachoriya Rahul and Sharma Ratnesh
Department of Pharmaceutics, V.N.S Institute of Pharmacy, Neelbud, Bhopal (M.P.) India
*Corresponding Author
DOI No: Not Available

The nasal mucosa deliberated as a potential administration route. Because of large surface area, porous endothelial membrane, rapid blood flow, first pass metabolism avoidance and quick accebility the drug absorption has been faster and also higher. Protein and peptides, low molecular weight polar molecules antiparkinson’s drugs and macromolecular polysaccharides. The major hurdle in nasal route of administration is the poor contact of formulation with mucosa of nose. But using absorption enhancer and mucoadhesive polymer the increase in residence time of drug in nasal mucosa. Many researchers became interested in the nasal route for the systemic delivery of medication due to high degree of vascularization and permeability.
Nasal Medication: A Potential Alternative Route.
Sharma Akshat, Pachoriya Rahul, Sharma Ratnesh. Nasal Medication: A Potential Alternative Route. Research J. Pharm. and Tech. 4(2): February 2011; Page 189-196.
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