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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   271-272

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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UV- Spectrophotometric Determination of Metoprolol Succinate



Address:   Verma Navneet*1,2, Ghosh A.K.1 and Chattopadhyay P.3
1College of Pharmacy, IFTM, Moradabad (U.P.)
2Institute of Pharmacy, Bhagwant University, Ajmer (Raj)
3Defence Research Laboratory, Tejpur (Assam).
*Corresponding Author
DOI No: Not Available

ABSTRACT:
A new, simple, specific, sensitive, rapid and economical procedure has been developed for simultaneous estimation of Metoprolol Succinate in its dosage form. The method is based on the ultraviolet absorbance maxima of the above drug at 222 nm. The drug obeyed Beer's law in the concentration range of 2-16 µg/ml with molar absorptivity of 3.67 x 104 l/mol.cm in methanol. The proposed methods were successfully applied for the determination of drug in commercial tablet preparations. The results of the analysis have been validated statistically and by recovery studies.
KEYWORDS:
Estimation, Metoprolol Succinate, Beer’s law.
Cite:
Verma Navneet, Ghosh A.K., Chattopadhyay P. UV- Spectrophotometric Determination of Metoprolol Succinate. Research J. Pharm. and Tech. 4(2): February 2011; Page 271-272.
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