List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   279-285

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Synthesis, Spectral Characterization and Pharmacological Screening of 1-Methylene-4-(5-(4-(Phenylamino)Phenyl)-1,3,4-Thiadiazol-2-Yl) Thiosemicarbazide Derivatives.



Address:   Anoop Singh1* and A.C.Rana2
1Dept. of Pharmaceutical Chemistry, Bhupal Noble’s College of Pharmacy, Udaipur (Rajasthan) India-313001
2Rayat Institute of Pharmacy, Rail Majra, Ropar (Punjab) India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Recently a series of 1-methylene-4-(5-(4-(phenylamino)phenyl)-1,3,4-thiadiazol-2-yl)thiosemicarbazide derivatives were synthesized and their pharmacologically evaluated for antimicrobial activities. The purpose of this study was to evaluate the potency of the title compounds on bacterial and fungal activities by varying the substituted in the 1-methylene-4-(5-(4-(phenylamino)phenyl)-1,3,4-thiadiazol-2-yl)thiosemicarbazide derivatives. All compounds of this series showed promising antimicrobial activities. It was found that some of these compounds possess marked antifungal and antibacterial properties comparable in efficiency to the reference drug Flukanazole and Ciprofloxacin respectively. In present study the structures of compounds were confirmed by UV, IR, 1H NMR.
KEYWORDS:
Salbutamol, microcapsules, in vitro controlled release, coacervation phase separation.
Cite:
Anoop Singh, ACRana. Synthesis, Spectral Characterization and Pharmacological Screening of 1-Methylene-4-(5-(4-(Phenylamino)Phenyl)-1,3,4-Thiadiazol-2-Yl) Thiosemicarbazide Derivatives. Research J. Pharm. and Tech. 4(2): February 2011; Page 279-285.
[View HTML]      [View PDF]



Visitor's No. :   199154