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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   167-174

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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New Technologies in Particulate Engineering for Pulmonary Delivery of Macromolecule

Address:   Pachoriya R and Sharma A
Department of Pharmaceutics, V.N.S Institute of Pharmacy, Neelbud, Bhopal (M.P.) India
*Corresponding Author
DOI No: Not Available

As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. Pulmonary delivery of macromolecule provides direct access to disease in the treatment of respiratory diseases, while providing an enormous surface area and a relatively low enzymatic, controlled environment for systemic absorption of medication. Macromolecular Porous microparticle possess densities sufficient small to create aerodynamic particle sizes in the range of 1-5 µm, and for deep lung delivery 1-3 µm. To impart favorable aerodynamic properties, an effervescent technology provides encapsulate drug efficiently, sustained drug release, create porous scaffold for tissue engineering application.
Macromolecule, Porous microparticle, Effervescent agents, Mucoadhesive agent, Dry powder inhaler.
Pachoriya R, Sharma A. New Technologies in Particulate Engineering for Pulmonary Delivery of Macromolecule. Research J. Pharm. and Tech. 4(2): February 2011; Page 167-174.
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