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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  12

Year :  2011

Pages :   1933-1940

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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A Review: Increasing Solubility of Poorly Soluble Drugs, by Solid Dispersion Technique



Address:   Nikam Shreya Pradeep*
Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon.
Corresponding author
DOI No: Not Available

ABSTRACT:
The solubility of a drug is one of the most important part of the drug formulation development. The effectiveness of drug is completely depends on the, solubility and bioavailability. This article reviews the various preparation techniques for solid dispersion and compiles some of the recent technology transfers. The different types of solid dispersions based on the molecular arrangement have been highlighted. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of carrier and methods of physicochemical characterization, alongwith an insight into the molecular arrangement of drugs in solid dispersions are also discussed.
KEYWORDS:
Solid dispersion, poorly soluble drug, carrier, solubility, bioavailability
Cite:
Nikam Shreya Pradeep. A Review: Increasing Solubility of Poorly Soluble Drugs, by Solid Dispersion Technique. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1933-1940.
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