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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  12

Year :  2011

Pages :   1891-1895

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Spectrophotometric Estimation of Etodolac and Thiocolchicoside in Tablet Dosage



Address:   R. Tiwari* and S. Pillai
Department of Pharmaceutical Chemistry, GRY Institute of Pharmacy “Vidhya Vihar” Borawan (Khargone), M.P-451 228, India
Corresponding author
DOI No: Not Available

ABSTRACT:
Simple, precise and economical spectrophotometric methods have been developed for the simultaneous estimation of Etodolac and Thiocolchicoside in combined tablet dosage form. The first method is based on the use of simultaneous equation, the second method is based on the use of absorbance ratio method and the third one is based on multicomponent mode method. Both the drugs obey the Beer’s law in the concentration ranges employed for these methods. The methods were validated by following the analytical performance parameters suggested by the International Conference on Harmonization. All validation parameters were within the acceptable range. The developed methods were successfully applied to estimate the amount of Etodolac and Thiocolchicoside in bulk and combined tablet dosage forms.
KEYWORDS:
Thiocolchicoside, Etoricoxib, simultaneous equation, absorbance ratio method, Multicomponent mode method.
Cite:
R. Tiwari, S. Pillai. Spectrophotometric Estimation of Etodolac and Thiocolchicoside in Tablet Dosage. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1891-1895.
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