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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  10

Year :  2011

Pages :   1567-1569

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Artesunate, Mefloquine, RP-HPLC and validation



Address:   Syeda Kulsum1, M. Padmalatha1, Eippa Kranthi Kumar 1, Madireddy Sruthi1 and G. Vidyasagar2*.
1Vijaya College of Pharmacy, Munaganur Village, Hayatnagar Mandal, Ranga Reddy District.AP
2Veerayathan Institute of Pharmacy, Jakhania Bhuj-Mandvi Road , Kutch ,Gujarat.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Two visible spectrophotometric methods have been developed for the determination of Irbesartan either in pure form or in their pharmaceutical formulations. The developed methods are based on reaction of naproxen with phenol red and bromocresol green. They are quantified spectrophotometrically at their absorption maximum at 422 nm (Method A) and 417nm (Method B). Beer’s law was obeyed in the concentration ranges of 60-80 µg/ml and 120-160µg/ml respectively. The colors were found to be stable for more than 4 hours. The proposed methods were successfully applied for determination of the naproxen in their pharmaceutical formulations and the results compared favorably to that of reference methods, hence are recommended for quality control and routine analysis.
KEYWORDS:
Spectrophotometer, Pharmaceutical dosage forms, Naproxen Sodium, Phenol Red and Bromocresol Green.
Cite:
Syeda Kulsum, M. Padmalatha, Eippa Kranthi Kumar, Madireddy Sruthi, G. Vidyasagar. Artesunate, Mefloquine, RP-HPLC and validation. Research J. Pharm. and Tech. 4(10): Oct. 2011; Page 1567-1569.
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