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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   4

Issue No. :  1

Year :  2011

Pages :   98-100

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Laxative and Anthelmintic Potential of Cassia alata Flower Extract



Address:   R.S. Adnaik, D.A. Bhagwat, I.D. Raut, S.K. Mohite and C.S. Magdum
Department of Pharmacology, Rajarambapu College of Pharmacy, Kasegaon, Tal. Walwa, Dist. Sangli 415 404, M. S., India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study was undertaken to screen the laxative and anthelmintic activity of Cassia alata flowers. The laxative activity was performed at a dose of 100 mg/kg and 200 mg/kg according to Cappaso et al in albino rats. Anthelmintic activity was evaluated separately on adult Indian earthworms, Pheritima posthuma by the method of Nargund. Agar-agar and piperazine citrate were used a standard drugs for laxative and anthelmintic activity respectively. The flower extract was found to produce significant (p>0.05) and dose-dependent increase in fecal output showing laxative activity; the 200 mg/kg dose being more potent. The extract was also found to paralyze and cause death of worms; showing significant anthelmintic activity.
KEYWORDS:
Laxative, Pheretima posthuma, Cassia alata Linn, agar-agar.
Cite:
RS Adnaik, DA Bhagwat, ID Raut, SK Mohite, CS Magdum. Laxative and Anthelmintic Potential of Cassia alata Flower Extract. Research J. Pharm. and Tech. 4 (1): January 2011; Page 98-100.
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