List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Antimicrobial Activity of Some Benzothiazolyl Pyrazolone Derivatives

Address:   *Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012.
DOI No: Not Available

A series of 2-(1H-Benzothiazol-2-ylmercapto/amino)-N-[1,5-dimethyl-2-(substituted phenyl)-3-oxo-2,3-dihydro-1H-pyrazol-4-yl] acyl amines (5a-o) have been synthesized. These structures are determined by the elemental analyses and spectral data (IR, 1H-NMR). These new derivatives are evaluated for in vitro antimicrobial activity against Staphylococcus aureus ATCC 3750, Salmonella typhi NCTC 786, Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.
Amino benzothiazole, anti–bacterial, anti–fungal, Mercapto benzothiazole, Pyrazolone.
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