List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Antimicrobial Activity of Some Benzothiazolyl Pyrazolone Derivatives



Address:   *Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012.
DOI No: Not Available

ABSTRACT:
A series of 2-(1H-Benzothiazol-2-ylmercapto/amino)-N-[1,5-dimethyl-2-(substituted phenyl)-3-oxo-2,3-dihydro-1H-pyrazol-4-yl] acyl amines (5a-o) have been synthesized. These structures are determined by the elemental analyses and spectral data (IR, 1H-NMR). These new derivatives are evaluated for in vitro antimicrobial activity against Staphylococcus aureus ATCC 3750, Salmonella typhi NCTC 786, Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.
KEYWORDS:
Amino benzothiazole, anti–bacterial, anti–fungal, Mercapto benzothiazole, Pyrazolone.
Cite:
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