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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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In Vitro Anthelmintic Activity of Roots of Abrus precatorius. Linn against Pheretima posthuma.



Address:   1Rajarambapu College of Pharmacy, Kasegaon. Tal- Walwa, Dist-Sangli, (MH) India. 2Sadhyadri College of Pharmacy, Methwade. Tal- Sangola, Dist-Solapur, (MH) India. 3Govindrao Nikam College of Pharmacy, Saverde. Tal- Chiplun, Dist- Ratnangeri. (MH) India.
DOI No: Not Available

ABSTRACT:
The present study was undertaken to evaluate anthelmintic activity of leaves of Abrus Precatorius Linn (Family - Fabacea) and its methanolic and aqueous extract against Pheretima posthuma. at Various concentrations (10-50 mg/ml) of methanolic and aqueous extracts were evaluated in the bioassay involving determination of time of paralysis (P) and time of death (D) of the worms. Piperazine citrate was used as standard anthelmintic drug and distilled water was used as control. The results of present study indicated that the methanolic and aqueous extract significantly exhibited paralysis (P<0.01) in worms in doses (10, 25and 50 mg/ml) and also caused death of worms especially at higher concentration of 50 mg/ml, as compared to standard drug.
KEYWORDS:
Anthelmintic, Abrus Precatorius, Pheretima posthuma, Piperazine citrate. 
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