Journal : Research Journal of Pharmacy and Technology
Volume No. : 3
Issue No. : 4
Year : 2010
Pages : 1235-1237
ISSN Print : 0974-3618
ISSN Online : 0974-360X
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Ameya G. Yadav, Vrushali N. Patil, S.V. Athlekar, A.S. Bobade, L.S. Patil and Abhay Chowdhary
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012.
*Corresponding Author
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DOI No:
ABSTRACT:
A series of 2-(1H-Benzothiazol-2-ylmercapto/amino)-N-[1,5-dimethyl-2-(substituted phenyl)-3-oxo-2,3-dihydro-1H-pyrazol-4-yl] acyl amines (5a-o) have been synthesized. These structures are determined by the elemental analyses and spectral data (IR, 1H-NMR). These new derivatives are evaluated for in vitro antimicrobial activity against Staphylococcus aureus ATCC 3750, Salmonella typhi NCTC 786, Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.
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KEYWORDS:
amino benzothiazole, anti–bacterial, anti–fungal, Mercapto benzothiazole, Pyrazolone.
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Cite:
Ameya G. Yadav, Vrushali N. Patil, S.V. Athlekar, A.S. Bobade, L.S. Patil, Abhay Chowdhary. Synthesis and Antimicrobial Activity of Some Benzothiazolyl Pyrazolone Derivatives. Research J. Pharm. and Tech.3 (4): Oct.-Dec.2010; Page 1235-1237.
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