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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   1209-1212

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Spectrophotometric Estimation of Risedronate Sodium in Bulk and Pharmaceutical Formulations using Multivariate Technique



Address:   S. Kathirvel, V. Sahiti and A. Suneetha*
Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur-2, A.P, India.
*Corresponding Author
DOI No:

ABSTRACT:
A sensitive, accurate and economical UV spectrophotometric method with multivariate calibration technique for the determination of risedronate sodium in bulk drug and pharmaceutical formulation has been described. This technique is based on the use of the linear regression equations by using relationship between concentration and absorbance at five different wavelengths. The results were treated statistically and were found highly accurate, precise and reproducible. The method is accurate, precise and linear within the range 10-60µg/ml. There was no interference from the excipients. This statistical approach gives optimum results for the eliminating fluctuations coming from instrumental or experimental conditions.
KEYWORDS:
UV Spectrophotometry; Multivariate Calibration; Pharmaceutical Formulation.
Cite:
S. Kathirvel, V. Sahiti, A. Suneetha. Spectrophotometric Estimation of Risedronate Sodium in Bulk and Pharmaceutical Formulations using Multivariate Technique. Research J. Pharm. and Tech.3 (4): Oct.-Dec.2010; Page 1209-1212.
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