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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   1132-1133

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Preclinical Evaluation of Antidiabetic Effect of Pedilanthus tithymaloides Extracts in Streptozotocin (STZ) Induced Diabetic Rats



Address:   S. Adhikary1*, C.C. Kandar1, P.K. Haldar2, A. Basu1 and S. Choudhury1
1Department of Pharmaceutical Chemistry
Institute of Pharmacy, Jalpaiguri
West Bengal
India – 735 101
2Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University, Kolkata – 700 032
*Corresponding Author
DOI No:

ABSTRACT:
Dried and powdered leaves of the plant Pedilanthus tithymaloides was extracted successively with chloroform and methanol using shoxlet extractor and the extracts were dried under reduced pressure at a temperature not exceeding 40°C. These extracts were subjected to different phytochemical tests and in the evaluation of antidiabetic potential on streptozotocin induced diabetic rats. Both the extract showed significant antidiabetic activity.
KEYWORDS:
Antidiabetic activity, streptozotocin induced diabetes, Pedilanthus tithymaloides.
Cite:
S. Adhikary, C.C. Kandar, P.K. Haldar, A. Basu, S. Choudhury. Preclinical Evaluation of Antidiabetic Effect of Pedilanthus tithymaloides Extracts in Streptozotocin (STZ) Induced Diabetic Rats. Research J. Pharm. and Tech.3 (4): Oct.-Dec.2010; Page 1132-1133.
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