List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   840-842

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Hepatoprotective Activity of an Aqueous Extract of Stem and Leaves of Boerhaavia diffusa Against Carbon Tetra Chloride Induced Hepatotoxicity in Rats



Address:   Venkatesh P.1*, Hepcy Kalarani D1 and Dinakar A.2
1P. Rami Reddy Memorial College of Pharmacy-Kadapa-516 003, Andhra Pradesh, India.
2Vagdevi College of Pharmacy and Research Centre, Nellore-524 004, Andhra Pradesh, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
An aqueous extract of stem and leaves of Boerhaavia Diffusa (AEBD) was studied for hepatoprotective activity against Swiss albino rats with liver damage induced by Carbon tetrachloride (CCl4) at two dose levels 150 and 300 mg kg-1. AEBD exhibited a significant protective action on the liver evident by a reduction in the elevated levels of serum lyosomal enzymes namely Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Alkaline Phosphatase (ALP) in CCl4 induced hepatotoxicity. Thus AEBD showed a dose dependent hepatoprotective activity.
KEYWORDS:
Hepatoprotective activity, AEBD, Carbon tetrachloride.
Cite:
Venkatesh P, Hepcy Kalarani D, Dinakar A. Hepatoprotective Activity of an Aqueous Extract of Stem and Leaves of Boerhaavia diffusa Against Carbon Tetra Chloride Induced Hepatotoxicity in Rats. Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 840-842.
[View HTML]      [View PDF]



Visitor's No. :   200192