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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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HPTLC Method for the Simultaneous Estimation of Aceclofenac and Diacerein in Tablets Dosage Forms



Address:   Department of Pharmaceutical Analysis, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore- 641 402. Tamilnadu, India.
DOI No: Not Available

ABSTRACT:
A new simple, accurate, precise HPTLC method has been developed for the simultaneous estimation of Aceclofenac and Diacerein in tablets formulation. In this method standard and sample solutions of Aceclofenac and Diacerein were applied on pre-coated silica gel G 60 f 254 TLC plate, and developed using chloroform: methanol (8: 2 v/v), as mobile phase. The drugs on plate were scanned at 256nm. The dynamic linearity range was 10-50 μg/spot for aceclofenac and 5-25 μg/spot for Diacerein. The method was validated for precision, accuracy and reproducibility.
KEYWORDS:
Simultaneous estimation, HPTLC, Aceclofenac and Diacerein.
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