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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Hepato-Protective Activity of the Water Extract of Launaea Intybacea (Jacq) Beauv in Paracetomol Induced Hepato-Toxicity in Albino Rats



Address:   1Agasti Arts, Comers and Dadasaheb Rupwate Science College, Akole, Dist-Ahmednagar, 422601(MH) India. 2Modern College of Pharmacy Nigdi Pune-411 044.
DOI No: Not Available

ABSTRACT:
The present study was conducted to evaluate the hepato-protective activity of water extract of aerial parts of Launaea intybacea are evaluated in paracetamol-induced hepatotoxicity in albino rats. Silymarin (200mg/kg) was given as reference standard. The water extract of aerial parts of Launaea intybacea have shown very significant hepatoprotection against paracetamol-induced hepatotoxicity in albino rats in reducing serum total bilirubin, SALP, SGPT , SGOT levels and liver homogenates LPO, SOD, CAT, GPX, GST and GSH levels.
KEYWORDS:
Launaea intybacea, hepatotoxicity, paracetomol and silymarin.
Cite:
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