List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Antiulcer Activity of Methanolic Extract of Cassia angustifolia Bark and Its Comparison with Ranitidine in Shay Rat.

Address:   1Sri Satya Sai college of Pharmacy, Sehore, M.P. 2Dept. of Pharmacy, Utkal University Bhubaneswar, 754004 3College of Pharmaceutical Sciences, Mohuda, Berhampur, Orissa.
DOI No: Not Available

Methanolic extract of Cassia angustifolia bark was tested for its anti gastric ulcer and compared with anti ulcer of ranitidine in shay rat model. Oral dose with 5mg/kg body weight of ranitidine showed complete absence of ulceration in shay rats. The anti gastric ulcer activity of Cassia angustifolia Methanolic extract (800mg/kg) body weight was found equal to the effect produced by 5mg/kg Ranitidine in this model. Oral administration of methanol extract (800 Mg. /Kg) Cassia angustifolia bark showed complete inhibition of ulceration and significant reduction in free acidity, Total acidity peptic activity and volume of gastric juice secreted were found.
Cassia angustifolia, total acidity, free acidity, peptic activity and ulcer index.
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