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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  2

Year :  2010

Pages :   402-405

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Anti-Hyperglycemic and Antioxidant Activities of the Mehari Choornam



Address:   Sanap GS*1, Sawant VA2, Shende VS2, Shid SL3, Borkar SN2, Tarannum S1, Dama GY2 and Suresh R2 1Ideal College of Pharmacy and Research, Kalyan.421301 India
2Sharadchandra Pawar College of Pharmacy Otur, Pune-412409 India
3S.S.J. College of Pharmacy, Asangaon, Thane (MS) India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Diabetes, the most prevailing metabolic disorder, is attracting present research attention towards it. In the present study, we have designed to evaluate the antihyperglycemic and antioxidant potential of Mehari choornam (POC), a poly herbal ayurvedic formulation, containing Curcuma longa, Emblica Officinalis and Syzigium cumini in different proportions as label claims. This combination of drug helps in reducing the blood glucose level in border-line diabetes and also acts as antioxidant thereby preventing end-organs complications. The effect of Mehari choornam on normoglycemic rats and on hyperglycemia induced with alloxan (120 mg/kg) on single and repeated administration of Mehari choornam was evaluated. The antioxidant potential of the extract was estimated in the heart and pancreas after repeated administration of Mehari choornam in alloxan induced diabetic rats. The results were satisfactory, as a significant decrease in the blood glucose levels after repeated administration was observed. The reversal of the decreased antioxidant enzyme levels in the heart and pancreatic tissues of diabetic rats suggest its efficacy against diabetes and oxidative damage.
KEYWORDS:
Mehari choornam, Diabetes, Alloxan, Gliclazide, antioxidants.
Cite:
Sanap GS, Sawant VA, Shende VS, Shid SL, Borkar SN, Tarannum S, Dama GY, Suresh R. Anti-Hyperglycemic and Antioxidant Activities of the Mehari Choornam. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 402-405.
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