List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  2

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Allready Registrered
Click to Login

Formulation and Evaluation of Loperamide Hydrochloride Mouth Dissolving Tablet by Using Super Disintegrants

Address:   1Shri Vishnu College of Pharmacy, Vishnupur, West Godavari, Bhimavaram – 534 202, Andhra Pradesh, India. 2Dep. of Pharmaceutical Analysis, Adhiparasakthi College of Pharmacy, Melmaruvathur, (T.N.), India- 603 319.
DOI No: Not Available

Loperamide hydrochloride 180 mg mouth dissolving tablet was prepared by using super disintegrants such as Sodium starch glycolate, Croscarmellose Sodium, Crospovidone at various concentration and Sucralose, aspartame used as sweetening agent. The excipients were used for this study was based on the compatibility studies. All the formulations were prepared by direct compression method. Among all the formulations Crospovidone at 10 mg/tablet gives 98 % drug release at 12th minute by UV method. It was considered as optimized batch. The optimized batch was passes all the evaluation parameters and stability studies. The final formulation were packed in blister package.
Loperamide hydrochloride, Sodium starch glycolate, Croscarmellose sodium, Crospovidone.
Not Available
[View HTML]     

Visitor's No. :   173288