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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  2

Year :  2010

Pages :   449-451

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Novel Visible Spectrophotometric Methods for Estimation of Fenoverine in Pharmaceutical Formulations



Address:   A Sreelakshmi*1, G Devala Rao2 and G Sudhakara Sai Babu2
1Department of Biotechnology, Montessori Mahila Kalasala, VIJAYAWADA-520 010, Andhra Pradesh, INDIA.
2K.V.S. R. Siddhartha College of Pharmaceutical Sciences, VIJAYAWADA-520 010- Andhra Pradesh, INDIA.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Fenoverine is an antispasmodic drug. Two simple, sensitive and accurate spectrophotometric methods have been developed for the determination of fenoverine in pure state and in its pharmaceutical formulations. The developed Method A is based on the formation of picrate salt between picric acid and free base of fenoverine and it shows maximum absorption at ? max 410 nm and Linearity in the range of 10-50 µg/mL. Method B involves reaction between free base of fenoverine and chloranilic acid. The developed chromogen in Method B shows maximum absorption at ? max 525 nm and Linearity in the range of 100-500 µg/mL. The results obtained were statistically evaluated and were found to be accurate and reproducible.
KEYWORDS:
Fenoverine, Spectrophotometric.
Cite:
A Sreelakshmi, G Devala Rao, G Sudhakara Sai Babu. Novel Visible Spectrophotometric Methods for Estimation of Fenoverine in Pharmaceutical Formulations. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 449-451.
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