List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Bioadhesive Drug Delivery Systems - Background, Applications and Trends



Address:   Department of Pharmaceutics, Y.B. Chavan College of Pharmacy, Dr. Rafiq Zakaria Campus, P.B. No. 33, Rouza Bagh, Aurangabad-431001, Maharashtra, India
DOI No: Not Available

ABSTRACT:
Mucoadhesive drug delivery systems have been used to improve and enhance drug bioavailability because the systems can contact with the absorption surface and prolong residence time resulting in a better absorption. Several polymers, particularly hydrophilic polymers containing numerous hydrogen bond (H-bond) forming groups (i.e. hydroxyl, carboxyl, amine and amide groups) have been investigated for mucoadhesive properties. The interaction between mucus and mucoadhesive materials is a result of physical entanglement and secondary bonding, mainly H-bonding and Van der Waals interaction.
KEYWORDS:
Mucoadhesive drug delivery, mucoadhesion, bioadhesive polymer
Cite:
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