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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   99-101

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Anti-inflammatory activity of Ethanolic Extract of the Roots of the Plant Caesalpinia sappan Linn.



Address:   Jennifer F1*, Thomas AK2, Fernandes R1 amd Subrhamanyam EVS1
1Department of Pharma. Chemistry, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte P.O, Mangalore -574160 India.
2Nirmala college of Pharmacy,Kerala India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
In the present study the anti-inflammatory activity of ethanolic extract of the roots of the plant Caesalpinia sappan. (Family: Caesalpiniaceae) was carried out. The preliminary phytochemical investigation revealed the presence of carbohydrates, proteins, triterpenoids, flavonoids, steroids and tannins. The ethanolic extract was subjected to anti-inflammatory study by Carrageenan induced paw edema model and Cotton pellet granuloma method in rats. The results of anti-inflammatory activities of ethanolic extract of the roots of the plant Caesalpinia sappan were compared with control and found to be statistically significant (P<0.01) at dose levels of 100mg/kg, 200mg/kg and 400mg/kg.
KEYWORDS:
Anti-inflammatory; cotton pellet granuloma; Caesalpinia sappan; Caesalpiniaceae.
Cite:
Jennifer F, Thomas AK, Fernandes R, Subrhamanyam EVS. Anti-inflammatory activity of Ethanolic Extract of the Roots of the Plant Caesalpinia sappan Linn. Research J. Pharm. and Tech. 3(1): Jan.-Mar. 2010; Page 99-101.
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