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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   95-98

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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The Analgesic Effect of Leucas aspera (Wild) Link Extract in Experimental Mice



Address:   Karthikeyan. M1* and Deepa Karthikeyan2
1Al Shifa College of Pharmacy, Poothavanam (P.O.),Kizhattur, Perinthalmanna, Malappuram Dist, Kerala-679325 , India.
2Nehru College of Pharmacy, Thiruvilwamala, Thrissur Dist., Kerala State- 680597, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Leucas aspera(Wild.)Link (Lamiaceae) is a plant used in traditional medicine for various disorders. The aim of this work was to evaluate the antinociceptive activity of the aqueous extract of Leucas aspera in animal models. In the acetic acid induced writhing model , the extract at a dose of 200 and 400 mg kg -1 body weight showed significant (p<0.01) inhibition of writhing response of 52.63 and 64.35 % respectively. In the hot plate test the extract produced a significant (p<0.01) increase in the latency in a dose related manner. This study established the analgesic properties of Leucas aspera (Wild.) Link.
KEYWORDS:
Leucas aspera, whole plant, aqueous extract, analgesic activity, writhing test, hot plate test.
Cite:
Karthikeyan M, Deepa Karthikeyan. The Analgesic Effect of Leucas aspera (Wild) Link Extract in Experimental Mice. Research J. Pharm. and Tech. 3(1): Jan.-Mar. 2010; Page 95-98.
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