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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Evaluation of Anti-inflammatory Activity of Flemingia strobilifera linn. Fabaceae



Address:   1Adhiparasakthi College of Pharmacy, Melmaruvathur-603319. 2School of Chemical and Biotechnology, SASTRA University, Thanjavur-613402.
DOI No: Not Available

ABSTRACT:
In this study, the anti-inflammatory effects of 200 and 400 mg/kg body weight of methanol and hydro-alcoholic extracts obtained from aerial parts of Flemingia strobilifera, the so-called MEFS and HAFS were investigated in Swiss albino mice respectively. The effects of MEFS and HAFS on the acute and sub acute phases of inflammation were studied in carrageenan induced paw oedema and cotton pellet-induced granuloma methods, respectively. In acute and sub acute phases of inflammation, amongst the two extracts selected for study the HAFS showed maximum inhibition of 37.06, 41.17 % (P < 0.01) at the dose of 400 mg/kg respectively. The results suggest that HAFS possess potent anti-inflammatory activity.
KEYWORDS:
Pithecellobium dulce, anti-inflammatory activity, carrageenan –induced paw edema
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