List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Biological Evaluation of Chloroacetyl Derivatives of Some Schiff’s Bases



Address:   K.M. College of Pharmacy, Uthangudi, Madurai – 625 107. TamilNadu, India.
DOI No: Not Available

ABSTRACT:
Synthesis of substituted 2-Azetidinone derivatives with chloro acetyl chloride along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and1HNMR spectroscopy. The antimicrobial activity of the synthesized compounds was evaluated, on Staphylococcus aureus, Pseudomonas aeruginosa. The anticonvulsant activity and anti inflammatory activities were also evaluated. The present investigation deals with the synthesized compounds possessing good anticonvulsant and anti inflammatory activity, moderate antibacterial activity.
KEYWORDS:
Chloro acetyl derivative, 2-Azetidionone, Antimicrobial activity, Anti convulsant activity, Anti inflammatory activity.
Cite:
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