Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   878-879

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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A Simple and Precise Method for the Estimation of Simvastatin in Formulations by UV-Visible Spectrophotometer



Address:   Hepcy Kalarani D1*, Venkatesh P1, Ravindra Reddy K1 and Dinakar A2
1P. Rami Reddy Memorial College of Pharmacy-Kadapa-516 003. Andhra Pradesh, India.
2Vagdevi College of Pharmacy and Research Centre- Nellore-524 004. Andhra Pradesh, India
*Corresponding Author
DOI No:

ABSTRACT:
A simple and precise spectrophotometric method in ultra violet region has been developed for the estimation of simvastatin in its pharmaceutical dosage forms. Simvastatin exhibited maximum absorbance at 237.8nm in ethanol. It obeys Beer’s law in the concentration range of 1-40mcg/ml. Results of the analysis were validated statistically and by recovery studies, repeatability studies.
KEYWORDS:
Simvastatin, UV, λmax
Cite:
Hepcy Kalarani D, Venkatesh P, Ravindra Reddy K, Dinakar A. A Simple and Precise Method for the Estimation of Simvastatin in Formulations by UV-Visible Spectrophotometer. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page 878-879.
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