Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   846-849

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis of Some New Bioactive Chalcones and Flavones



Address:   SS Mokle, MA Sayyed, AY Vibhute, SV Khansole, YS Nalwar and YB Vibhute*
Laboratory of Organic Synthesis, P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded 431602 (M.S.)
*Corresponding Author
DOI No:

ABSTRACT:
New chalcones (3a-g) were synthesized from 5-chloro-2-methoxybenzaldehyde (2) and halohydroxysubstitued acetophenones (1a-g) via Claisen-Schmidt condensation. Further new flavones (4a-g) were synthesized by oxidative cyclisation of chalcones (3a-g).The structure of synthetic compounds were confirmed by IR, 1H NMR and elemental analysis. These compounds were screened for their antibacterial activity and studied the effect on seed germination of wheat (Triticum aestivum).
KEYWORDS:
Chalcones, flavones, antibacterial activity, seed germination of wheat.
Cite:
SS Mokle, MA Sayyed, AY Vibhute, SV Khansole, YS Nalwar, YB Vibhute. Synthesis of Some New Bioactive Chalcones and Flavones. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page 846-849.
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