Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   830-832

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Anti-Inflammatory Activity of Some New Pyrimidine Derivatives



Address:   Ramesh B.1* and Babitha S.2
1Dept. of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102. Karnataka
1Dept. of Pharmacology, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102. Karnataka
*Corresponding Author
DOI No:

ABSTRACT:
Some new pyrimidine derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with guanidine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.
KEYWORDS:
Synthesis, Pyrimidines, Anti-inflammatory activity.
Cite:
Ramesh B., Babitha S.. Synthesis and Anti-Inflammatory Activity of Some New Pyrimidine Derivatives. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page 830-832.
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