Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   824-829

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Biological Evaluation of Chloroacetyl Derivatives of Some Schiff’s Bases



Address:   P Muthumani*, R Meera, Pratesh, N Chidambaranathan, P Devi and B Kameswari
K.M. College of Pharmacy, Uthangudi, Madurai – 625 107. TamilNadu, India.
*Corresponding Author
DOI No:

ABSTRACT:
Synthesis of substituted 2-Azetidinone derivatives with chloro acetyl chloride along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and1HNMR spectroscopy. The antimicrobial activity of the synthesized compounds was evaluated, on Staphylococcus aureus, Pseudomonas aeruginosa. The anticonvulsant activity and anti inflammatory activities were also evaluated. The present investigation deals with the synthesized compounds possessing good anticonvulsant and anti inflammatory activity, moderate antibacterial activity.
KEYWORDS:
Chloro acetyl derivative, 2-Azetidionone, Antimicrobial activity, Anti convulsant activity, Anti inflammatory activity.
Cite:
P Muthumani, R Meera, Pratesh, N Chidambaranathan, P Devi, B Kameswari. Synthesis and Biological Evaluation of Chloroacetyl Derivatives of Some Schiff’s Bases. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page 824-829.
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