Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   589-591

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Anti-Inflammatory Activity of Petroleum Ether Extract of Seeds of Ocimum Basilicum Linn



Address:   Pankaj Rakha*1, Manju Nagpal1, Sunil Sharma2 and Milind Parle2
1Rajendra Institute of Technology and Sciences, 4th mile stone, Hisar Road, Sirsa- 125055
2Dept. of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar- 125001.
*Corresponding Author
DOI No:

ABSTRACT:
In the present study we have studied the effect of petroleum ether extract of seeds of the plant Ocimum basilicum Linn. on acute phase of inflammation induced by carrageenan and formalin. The chronic phase of inflammation was studied using cotton pellet granuloma technique. The increase in paw thickness was measured using digital vernier caliper after 1, 2, 3 and 4h of injection. Petroleum ether extract at dose of 400 mg/Kg significantly inhibited acute phase of inflammation induced by carrageenan and formalin. The decrease in the weight of granuloma was also found by the extract at dose of 400mg/kg. The study clearly shows that the petroleum ether extract of seeds of Ocimum basilicum Linn. possesses significant anti-inflammatory activity.
KEYWORDS:
Anti-inflammatory, carrageenan, formalin, granuloma.
Cite:
Pankaj Rakha, Manju Nagpal, Sunil Sharma, Milind Parle. Anti-Inflammatory Activity of Petroleum Ether Extract of Seeds of Ocimum Basilicum Linn. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 589-591.
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