Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   585-588

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Formulation and evaluation of Isoniazide Dispersible tablets using Natural substances as Disintegrants



Address:   BS Kuchekar, SR Pattan, RK Godge, RB Laware, NS Dighe SK Parjane and AN Merekar*
Dept. of Pharmaceutics. Pravara Rural College of Pharmacy, Pravaranagar.
*Corresponding Author
DOI No:

ABSTRACT:
Dispersible tablets of Isoniazide were prepared using natural substances as disintegrant such as Ispaghula husk powder, Cassia tora powder, Cassia tora powder (defatted), Cassia nodosa powder in different concentration by direct compression method. Formulations were evaluated for the standard of dispersible tablets and were compared with marketed products. It was observed that all the formulations were acceptable with reasonable limits of standard required for dispersible tablets. The study reveals that natural gums used as disintegrants were effective in low concentration.
KEYWORDS:
Dispersible tablet, direct compression, Isoniazid, natural disintegrants.
Cite:
BS Kuchekar, SR Pattan, RK Godge, RB Laware, NS Dighe SK Parjane, AN Merekar. Formulation and evaluation of Isoniazide Dispersible tablets using Natural substances as Disintegrants. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 585-588.
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